Novelist Larry Donner (Billy Crystal) struggles with writer's block due to his resentment towards his ex-wife Margaret (Kate Mulgrew), who stole his book and garnered mainstream success and critical acclaim with it. Owen Lift (Danny DeVito) is a timid, middle-aged man who still lives with his overbearing, abusive mother (Anne Ramsey). Owen fantasizes of killing his mother but can't summon the courage to bring his desires into fruition. As a student in Larry's community college writing class, Owen is given advice by Larry to view an Alfred Hitchcock film to gain some insight into plot development. He sees Strangers on a Train, in which two strangers conspire to commit a murder for each other, figuring their lack of connection to the victim will, in theory, establish a perfect alibi. Having overheard Larry's public rant that he wish his ex-wife dead, Owen forms a plan to kill Margaret, believing that Larry will respond by killing his mother. He tracks Margaret down to Hawaii and follows her onto a cruise ship, apparently pushing her overboard while she tries to retrieve an earring that fell out. Owen returns from Hawaii to tell Larry of Margaret's death and that Larry now "owes" him the murder of his mother, lest he inform the police Larry was the killer. After having spent the night drinking alone during the hours of Margaret's disappearance, Larry panics because he lacks a sufficient alibi. That, along with a news report announcing the police suspect foul play, convinces Larry he's the prime suspect. He decides to stay with Owen and his mother in an attempt to hide from the police. Larry meets Mrs. Lift, but despite her harsh treatment of him he refuses to kill her. Eventually, when Mrs. Lift drives Owen to the breaking point, Larry finally relents and agrees to go through with the murder. After two unsuccessful attempts, Larry flees the Lift home when Mrs. Lift recognizes him as a suspect from a news broadcast about his ex-wife's disappearance. He boards a train to Mexico and, surprisingly, Owen and Mrs. Lift come along so as to avoid having to lie for him. During the journey, Larry's patience with Mrs. Lift reaches its pinnacle when she impolitely gives him advice on writing. He follows her to the caboose with the intent of throwing her from the train, but stops short when she almost falls off on her own. Owen begins having second thoughts about having his mother killed and comes to help Larry rescue her. Mrs. Lift is grateful at her son for saving her, but unappreciative of Larry's help and kicks him, resulting in him losing his balance, landing on the tracks, and breaking his leg. During his recovery in the hospital, Larry discovers Margaret is still alive; she simply fell overboard by accident and was rescued by a Polynesian fisherman whom she has decided to marry. Much to his annoyance, Larry learns Margaret plans to sell the rights of her ordeal for $1.5 million dollars. On the advice of a fellow patient, Larry chooses to free himself of his obsession with his ex-wife and instead focus on his own life, thereby freeing him of his writer's block. A year later, Larry has finished a novel based on his experiences with Owen and Mrs. Lift entitled Throw Momma from the Train. Owen visits and informs him that his mother has died (of natural causes) and that he's going to New York City for the release of his own book. Unfortunately, Owen reveals his book is also about their experiences together. Thinking his book has been scooped, an enraged Larry proceeds to strangle him, but stops when Owen shows him the book is a children's pop-up book called, Momma, Owen, and Owen's Friend Larry with the story drastically altered to be suitable for children. Months later, Larry, Owen, and Larry's girlfriend Beth (Kim Greist) vacation together in Hawaii, reflecting on the final chapter of Larry's book. Larry and Owen's books have now become best-sellers, making them both successful writers as well as close friends.
斯科特·阿金斯,约翰·汉纳,拉什纳·林奇,艾略特·詹姆斯·朗格里奇,弗朗茨·德拉姆,伊莎贝尔·艾伦,萨莉·柯莱特,杰森·马扎,汤米·弗拉纳根,山姆·哈兹尔丁,安迪·奥修,Shirin Daryaie,马丁·福特,Finley Sebastian Pearson,Geraldine Sharrock,露丝·霍洛克斯
布朗什·加丁,德尼·波达利德斯,科琳娜·马谢罗,文森特·拉科斯特,伯努瓦·波尔沃德,杰基·贝约尔,Jean-Louis Barcelona,让·杜雅尔丹,Lucas Mondher,Miss Ming,Monique Leroux,Jo Dahan,Suzy,樊尚·德迪安,Victor Kervern,菲利普·雷博,伯利·兰内尔,米歇尔·维勒贝克,埃文特·斯特朗,丹尼斯·欧哈拉,古斯塔弗·科文
孔璨,洪殷基,李承铉,崔东久
纳西姆·斯艾哈迈德,弗雷德·特斯托,茱莉·费瑞尔,海迪·布奇纳法,Aymen Rahoui
成龙,魏翔,史策,韩彦博,贾冰,安地,马铁摩,莎莎,芮丹尼,诺克,图林,伊万·波诺马连科,奥梅尔·尤祖亚克
伊莎贝尔·于佩尔,伊波利特·吉拉尔多,莉莲娜·罗维埃,伊里斯·布里,卡梅尔·古恩福,亚辛·侯伊卡,Farida Ouchani,Nadja Nguyen,Rebecca Marder,Rachid Guellaz,Mourad Boudaoud,Youssef Sahraoui,Abbes Zahmani,Yann Sundberg,Michaël Louchart,Raphaël Quenard
裴淳华,彼特·丁拉基,艾莎·冈萨雷斯,黛安·韦斯特,克里斯·梅西纳,小伊塞亚·维特洛克,梅肯·布莱尔,艾丽西亚·维特,达米安·杨,尼古拉斯·罗根,利兹·恩格,乔治亚·莱曼,克里斯·埃弗里特,何塞·冈斯·阿尔维斯,凯文·芬内西,珍妮尔·费格利,杰米·加扎里安,阿德里安·M·蒙波因特
艾丽森·汉妮根,本·施瓦茨,丹尼·朴迪,凯特·米库奇,鲍比·莫尼汉,本杰明·埃文·安斯沃思,约翰·卡西尔
埃里克·南乔,萨利夫·西塞,爱德华·苏皮斯,阿斯玛·梅萨乌丁,安娜·布拉戈耶维奇,露西·加洛,马丁·梅斯尼尔,尼古拉斯·皮特里,塞西尔·弗耶,乔丹·鲁斯,玛丽·安妮·奎林,西尔万·凯莱,罗杰·梅勒,科洛·莱维,伊琳娜·布拉克·拉珀鲁萨斯
哈德莉·罗宾逊,劳伦·蔡,尼科·希拉加,帕特里克·施瓦辛格,西德尼·帕克,安杰利卡·华盛顿,J·J·托塔,艾米·波勒,伊克·巴里霍尔兹,马西娅·盖伊·哈登,约瑟芬·兰福德,Joshua Walker,克拉克·格雷格,罗恩·帕金斯,亚伦·霍利戴,维克托·沃尔夫,格雷格·波勒,凯文·多尔夫,柯瑞·福格尔玛尼斯,布兰迪·赖特